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When Noroxin is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. When taking antibiotics known as quinolones, including Cipro, Floxin, and Noroxin, you should take Videx at least 6 hours before the antibiotic, or wait for 2 hours after it. Caution should be used when prescribing Noroxin to elderly patients, especially those on corticosteroids. It is not known if Noroxin will harm your unborn child. It is not known if Noroxin is safe and works in children under 18 years of age. Do not take more than 2 doses of Noroxin in one day. It is not known if Noroxin passes into breast milk. Tablets Noroxin should be taken with a glass of water. Therefore, precaution should be taken when using Noroxin concomitantly with drugs that can result in prolongation of the QTc interval (e. Talk with your healthcare provider about whether you should continue to take Noroxin. This will help make sure that all of the bacteria are killed and lower the chance that the bacteria will become resistant to Noroxin. Patients should be informed of this potential side effect and advised to discontinue Noroxin and contact their healthcare provider if any symptoms of tendinitis or tendon rupture occur (see Boxed Warning; WARNINGS; and ADVERSE REACTIONS, Post-Marketing). Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Noroxin or other antibacterial drugs in the future. After a single 400-mg dose of Noroxin, mean antimicrobial activities equivalent to 278, 773, and 82 μg of norfloxacin/g of feces were obtained at 12, 24, and 48 hours, respectively. This is especially important if you are taking an antibiotic such as ciprofloxacin (Cipro), demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), norfloxacin (Noroxin), ofloxacin (Floxin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap). Children have a higher chance of getting bone and joint (musculoskeletal) problems while taking Noroxin. If this happens, Noroxin and other antibiotic medicines may not work in the future. Noroxin should be discontinued if the patient experiences pain, swelling, inflammation or rupture of a tendon. Noroxin can cause side effects that may be serious or even cause death. Do not take two doses of Noroxin at the same time. Noroxin and other medicines6 can affect each other causing side effects. Caution should be exercised when using quinolones, including Noroxin, in patients with myasthenia gravis (see ADVERSE REACTIONS). 8338 — Tablets Noroxin 400 mg are white to off-white, oval shaped, film-coated tablets, coded 705 on one side and plain on the other. Therefore, Noroxin should be used with caution in individuals receiving NSAIDS concomitantly. See the list of ingredients in Noroxin at the end of this Medication Guide. Taking an NSAID while you take Noroxin or other fluoroquinolones may increase your risk of central nervous system effects and seizures. Stop taking Noroxin until tendinitis or tendon rupture has been ruled out by your healthcare provider. You and your healthcare provider should decide whether you will take Noroxin or breast-feed. You may need a lower dose of Noroxin if your kidneys do not work well. Talk to your healthcare provider about the risk of tendon rupture with continued use of Noroxin.



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